Possible Interaction: Nicotine and Calcium Supplement

“ Nicotine was found to induce rises in calcium in a smaller proportion of LDT cells in PNE mice aged 7–15 days and smaller rises in calcium in PNE animals from postnatal ages 11–21 days when compared with age-matched control animals.”

“Repeated administration of nicotine led to a ca.”

“ Nicotine acutely raises intracellular calcium ([Ca2+]i) in T cells, but the mechanism of this response is unclear.”

“Conclusions: Nicotine can increase the expression of TRPC6 protein, SOCE and ROCE level, and increase the intracellular calcium concentration by upregulating the expression of α7nAChR protein, thereby promoting smooth muscle cell contraction.”

“In addition, nicotine caused a dose-dependent decrease in alizarin red staining for calcium and staining for ALP.”

“ Nicotine triggered influx of calcium in the 273T NSCLC cell line, suggesting that L-type calcium channels were activated.”

“Addition of nicotine to a repairing wound resulted in a dose-dependent transient increase of intracellular calcium in migrating cells that line the wound edge.”

“Mineralized nodule formation and calcium content in mineralized nodules were remarkably suppressed by nicotine on days 10 and 14 of culture, respectively.”

“ Nicotine transiently increased the intracellular calcium concentration to higher levels in leukemic cells than in normal leukocytes.”

“As to tabagism, experiments in animals have shown that nicotine can increase calcium content of the arterial wall, and clinical studies have demonstrated that cigarette smoking induces peripheral vasoconstriction, with consequent increase in blood pressure levels.”