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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Niacin
supplement:
Vitamin B 12
Research Papers that Mention the Interaction
“In men, pork and beef; squid, octopus, shrimp, and clams; eggs; mushrooms; Japanese-style sweets; ice cream; bread; Chinese … acid, polyunsaturated fatty acid (PUFA), n-3 PUFA, n-6 PUFA, cholesterol, vitamin D, vitamin B2, vitamin B6, vitamin B12, niacin , pantothenic acid, magnesium, phosphorus, and … <0.05 for all).”
Interactions between psychological stress and drinking status in relation to diet among middle-aged men and women: a large-scale cross-sectional study in Japan.“The degradation losses of cyanocobalamin in the presence of increasing concentrations of thiamin and niacin ranged between 6%-13% and added sorbitol significantly prevented the loss of cyanocobalamin (p<0.05).”
Sorbitol enhances the physicochemical stability of B12 vitamers.“The overlapping of the absorption … of thiamine hydrochloride, nicotinamide , pyridoxine hydrochloride and ascorbic acid with cyanocobalamin in the UV region and those of riboflavin in the UV and visible region may influence the rate of photolysis of cyanocobalamin in aqueous solution due to mutual interaction on exposure to light.”
“There are several previously reported observations which suggest that this rate might be much slower for cyanocobalamin than for some of the other watersoluble vitamins, such as thiamine, nicotinic acid (niacin), and ascorbic acid.”
“ Vitamin B12 has been found to deteriorate progressively in association with aneurine and nicotinamide in solution over a pH range of 4 to 4·5.”
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