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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Niacin
Research Papers that Mention the Interaction
“ Nicotinamide effectively inhibited ANG II-induced renal vasoconstriction in WT mice (P < 0.001), but had no effect on renal responses to ANG II in CD38-/- mice (P > 0.5).”
Mice lacking the ADP ribosyl cyclase CD38 exhibit attenuated renal vasoconstriction to angiotensin II, endothelin-1, and norepinephrine.“Transient vasoconstrictor responses lasting up to 10 min were induced with bolus injections (10 microliters) of phenylephrine, at concentrations ranging from 10(-5) … with PE (5 x 10(-6) M) or raising the K+ concentration of the Krebs' solution to 122 mM. The addition of NA … transient vasoconstrictor responses ….”
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