“In conclusion, tramadol inhibits catecholamine secretion partly by inhibiting nicotinic AChR functions in a naloxone‐insensitive manner and α7 receptors are one of those inhibited by tramadol.”
“ Tramadol inhibited both α‐bungarotoxin‐sensitive and ‐insensitive nicotinic currents in bovine adrenal chromaffin cells.”
“ Tramadol inhibited nicotinic currents carried by α7 receptors expressed in Xenopus oocytes.”