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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Niacin
drug:
Thioguanine
Research Papers that Mention the Interaction
“Objectives—Extended-release niacin effectively lowers plasma TG levels and raises plasma high-density lipoprotein (HDL) cholesterol levels, but the mechanisms responsible for these effects are unclear.”
Extended-Release Niacin Alters the Metabolism of Plasma Apolipoprotein (Apo) A-I and ApoB-Containing Lipoproteins“The inhibition of TG synthesis by niacin results in accelerated intracellular hepatic apo B degradation and the decreased secretion of VLDL and LDL particles.”
“ Nicotinic acid increases HDL cholesterol by 15–35%, lowers plasma TG by 25–30% and LDL cholesterol by 15–20%.”
Treating diabetic dyslipidemia: What have we learnt from recent clinical trials?
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