“ Nicotinamide and nicotinic acid--vitamin B₃ components--promote S. tsukubaensis growth most probably due to the stimulation of NAD/NADP biosynthesis.”
“The enrichment of the fermentation medium in pyridine-2-carboxylic acid (picolinic acid), …-2-carboxylic acid (pipecolic acid), pyridine-3-carboxylic acid (nicotinic acid) or pyridine-3-carboxylic acid amide (nicotinamide) caused significant growth of the productivity of tacrolimus : 7-fold, 6-fold, 3-fold and 5-fold, respectively.”