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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Niacin and Tacrine

supplement:

Niacin

drug:

Tacrine

Research Papers that Mention the Interaction

In receptor competition studies with3H-nicotine,3H-ACh and3H-quinuclidinyl benzilate (3H-QNB) as receptor ligands, THA interfered with both nicotinic and muscarinic receptor ligand binding, while physostigmine had much less effect.
Journal of Neural Transmission  •  2005  |  View Paper
Repeated administration of tacrine resulted in decreased binding to high-affinity choline uptake, nicotinic and M2-muscarinic acetylcholine receptor sites in a number of cortical regions, while reductions in M1-muscarinic receptor binding were restricted to the cingulate and entorhinal cortex as well as caudate-putamen.
Neurochemistry International  •  1997  |  View Paper