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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Niacin
drug:
Somatostatin
Research Papers that Mention the Interaction
“Although plasma glucose concentration fell significantly in response to both NA and NA + SRIF , the effect of NA + SRIF was approximately twice as great as that seen with NA alone.”
Effect of nicotinic acid on plasma glucose concentration in normal individuals.“ Somatostatin reversibly inhibited the nicotinic cholinoceptor-mediated depolarization and inward current induced by acetylcholine.”
Somatostatin inhibits nicotinic cholinoceptor mediated-excitation in rat ambigual motoneurons in vitro“The present results provide the first direct evidence at a cellular level that substance P and somatostatin act as inhibitory modulators of the nicotinic ACh response, and support a role for these peptides as inhibitory neuromodulators at nicotinic receptor sites in the nervous system.”
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