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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Niacin
supplement:
Riboflavin
Research Papers that Mention the Interaction
“In men, pork and beef; squid, octopus, shrimp, and clams; eggs; mushrooms; Japanese-style sweets; ice cream; bread; …, carbohydrate, monounsaturated fatty acid, polyunsaturated fatty acid (PUFA), n-3 PUFA, n-6 PUFA, cholesterol, vitamin D, vitamin B2, …, niacin , pantothenic acid, magnesium, phosphorus, and zinc … interaction <0.05 for all).”
Interactions between psychological stress and drinking status in relation to diet among middle-aged men and women: a large-scale cross-sectional study in Japan.“Urine analysis showed vitamin B2 and niacin of urban mothers and children were significantly higher than that in rural area (P < 0.05).”
“Besides, initial consumption of vitamin B2 was not sometimes considered, but deficiency in riboflavin caused considerable impairments of vitamin B6 and niacin metabolism.”
“ Nicotinamide prevented formation of the mononucleotide in vivo.”
Mechanism of action of 2-amino-1,3,4-thiadiazole (NSC 4728).“Direct transfer of the hydrogen is seen between the nicotinamide and deazariboflavin in both reaction directions.”
“Favorable van der Waals interaction energy between riboflavin and nicotinamide plays an important role in the 1:1 or 1:2 complex formation between drug and hydrotrope molecules.”
“The analyses of orientation distributions and distance measurements reveal that the riboflavin and nicotinamide molecules form 1:2 sandwich complexes.”
Hydrotropic Solubilization of Sparingly Soluble Riboflavin Drug Molecule in Aqueous Nicotinamide Solution.“We use nicotinamide (vitamin B3) as a hydrotropic agent to enhance the water solubility of flavin mononucleotide.”
“ NA is involved as an electron acceptor during the sequence of reactions and thus enhances the rate of photolysis of RF.”
“The second-order rate constants (k2) for the bimolecular interaction of RF and NA range from 0.54 (pH 1.0) to 9.66 M–1 min–1 (pH 12.0).”
“It is suggested that the biological synthesis of reduced form of flavin mononucleotide (FMNH2), an essential coenzyme for the activities of biodesulfurization enzyme Dsz C and A, might be enhanced by nicotinamide and riboflavin, which was responsible for the increased SA of R. erythropolis USTB-03.”
“The complexation hypothesis is tested by looking at nicotinamide's ability to quench riboflavin fluorescence and by examining changes in the UV/Vis spectrum of riboflavin upon addition of nicotinamide.”
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