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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Niacin
drug:
Physostigmine
Research Papers that Mention the Interaction
“3 Nicotinic blockade produced by superfusion with physostigmine (30 μm) was insurmountable when tested against nicotine (0.1–100 μm).”
Blockade of nicotinic responses by physostigmine, tacrine and other cholinesterase inhibitors in rat striatum“Single-channel recordings showed that physostigmine decreases conductance and open times of the channels activated in the presence of ACh and in addition has an agonistic property on the nicotinic AChR. VX, on the other hand, only shortened the open times of ACh-activated channels without affecting the conductance.”
“The effects in the accessory optic system apparently result from nicotinic actions of physostigmine.”
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