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Discover Supplement-Drug Interactions

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Last Updated: 6 months ago

Possible Interaction: Niacin and Phosphorus, Dietary

supplement:

Niacin

Research Papers that Mention the Interaction

Limited data from pilot studies in patients with CKD stages 3-4 suggest that phosphate binders, low phosphate diets, or vitamin B3 derivatives, such as niacin or nicotinamide, may reduce dietary phosphate absorption and serum phosphate and FGF23 levels.
Journal of the American Society of Nephrology : JASN  •  2015  |  View Paper
Dietary phosphate absorption can be moderated by emphasizing plant-based dietary choices (which provide phosphate in less bioavailable forms); avoidance of processed foods containing inorganic phosphate food additives; and by ingestion of phosphate-binder drugs, magnesium supplements, or niacin , which precipitate phosphate or suppress its gastrointestinal absorption.
Nutrition  •  2014  |  View Paper
Minimizing the absorption of dietary phosphate may also be helpful in this regard, particularly in renal failure, and it can be achieved with plant–based dietary choices, avoidance of phosphate additives, and administration of pharmaceutical phosphate binders, supplemental magnesium, and niacin.
Postgraduate medicine  •  2014  |  View Paper
We conclude that nicotinamide and PTH reverse the effects of dietary phosphate deprivation by decreasing the tubular capacity for phosphate transport.
The American journal of physiology  •  1983  |  View Paper