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Last Updated: 2 years ago

Possible Interaction: Niacin and Phospholipids

supplement:

Niacin

Research Papers that Mention the Interaction

RESULTS Ni otinic acid tr eatment raised total HDL cholesterol and pho spholipids, H DL2 levels as well as HDL particle size.
Revista medica de Chile  •  2015  |  View Paper
In cultured human hepatocytes (HepG2), niacin increased: association of apoA-I with phospholipids and cholesterol by 46% and 23% respectively, formation of lipid-poor single apoA-I molecule-containing particles up to ∼ 2.4-fold, and pre β 1 and α migrating HDL particles.
Niacin dose-dependently stimulated the cell efflux of phospholipid and cholesterol and increased transcription of ABCA1 gene and ABCA1 protein.
Journal of Lipid Research  •  2012  |  View Paper
These results suggest that nicotinic acid significantly protects the arrested-reperfused myocardium by a) preventing elevation of myocardial fatty acid levels, b) stimulating glycolysis by limiting fatty acid oxidation, c) inhibiting degradation of membrane phospholipids , and d) preventing accumulation of fatty acid metabolites with harmful detergent properties.
While nicotinic acid inhibited β-oxidation during pre-ischemia and reperfusion, it also prevented the degradation of membrane phospholipids.
Basic Research in Cardiology  •  2005  |  View Paper
We conclude that nicotinamide enhances brain choline concentrations by mobilising choline from choline-containing phospholipids , presumably via activation of phospholipase A2, while the formation of NMN does not contribute to this effect.
Neuroscience Letters  •  1998  |  View Paper
Similarly, phospholipid levels in niacin + AD and taurine + niacin + AD groups were decreased significantly compared to AD alone.
The Journal of pharmacology and experimental therapeutics  •  1992  |  View Paper
The diet supplemented with taurine (2.5%), niacin (2.5%), or taurine (2.5%) + niacin (2.5%) also reduced AD-induced increases in lung collagen accumulation, phospholipids , MDAE and SOD activity.
Advances in experimental medicine and biology  •  1992  |  View Paper
The intensity of methylation of choline-containing phospholipids under the effect of nicotinic acid lowers in all the tissues under study.
Ukrains'kyi biokhimichnyi zhurnal  •  1975  |  View Paper
of nicotinic acid caused significant decreases of serum cholesterol and phospholipids in thyroidectomized dogs and in normal dogs, both on low and on high-fat diets.
Metabolism: clinical and experimental  •  1966  |  View Paper