supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago
supplement:
Niacin
drug:
Phenylephrine
Research Papers that Mention the Interaction
“Moreover, nicotinamide significantly reduced the sensitivity to phenylephrine in Ca2+-free Krebs' solution (P < 0.0152).”
Nicotinamide-inhibited vasoconstriction: lack of dependence on agonist signalling pathways.“Continuous perfusion of NA reduced the dose response to PE by 77%.”
“ NA is effective against contractile agonists such as phenylephrine , vasopressin and high KC1 concentrations which activate various pathways in vascular smooth muscle.”
“ NA at a concentration of 8.2 mM reduced the constrictions produced by phenylephrine (PE) by 2-fold in both normal epigastric arteries and those that had been supplying p22 tumours in BD9 rats.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback