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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Niacin
drug:
Nicorandil
Research Papers that Mention the Interaction
“Advanced age and accumulation of nicotinic acid in tissues may be contributory to the risk of developing ocular ulcerations from nicorandil.”
Conjunctival and corneal ulceration associated with nicorandil“Experimental evidence showed that N-(2-hydroxyethyl) nico-tinamide, the major metabolite of nicorandil in rats, and nicotinamide (niacinamide) itself, indeed inhibited nicorandil elimination.”
A Modified Product Inhibition Model Describes the Nonlinear Pharmacokinetics of Nicorandil in Rats
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