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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Niacin
drug:
Hexamethonium
Research Papers that Mention the Interaction
“Twenty‐three (out of twenty‐five neurones tested) received nicotinic fast excitatory synaptic inputs (fast e.p.s.p.s) that were blocked reversibly by hexamethonium and mimicked by acetylcholine.”
Intracellular recordings from myenteric neurones in the human colon.“ Hexamethonium , a blocker of nicotinic ganglionic transmission, was able to prevent the AITC-evoked inhibitory effect, an effect that was also observed with the opioid antagonist naloxone.”
Effects of Allyl Isothiocyanate, Acetaminophen, and Dipyrone in the Guinea-Pig Ileum“ Hexamethonium , a blocker of nicotinic ganglionic transmission, at 300 μmol/l and 1 mmol/l augmented the twitch contractions by 21% and 35%, respectively.”
“When nicotinic and muscarinic receptors were blocked by hexamethonium and atropine, 20 Hz stimulation for 10 s initiated a sEPSP in all innervated neurones.”
“These effects were blocked by the application of the nicotinic antagonist hexamethonium.”
“The nicotinic antagonist Hexamethonium reduced the evoked flow by approximately 50% (30 mg/kg), while the muscarinic antagonist Atropin did not influence the stimulation evoked blood flow.”
“ Nicotinic blockade by adding hexamethonium into the perfused solution inhibited long-term potentiation induction.”
“3 The occlusive effects of nicotinic agonists on ATP‐gated currents were blocked by the nicotinic receptor/ion channel blocker hexamethonium (150 μM).”
“ Nicotinic and muscarinic M1 receptors were blocked with hexamethonium and pirenzepine, respectively.”
“In contrast, when the nicotinic positive feedback was prevented by hexamethonium , atropine failed to enhance the release.”
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