“A high dose of niacin increased lung NAD+, nicotinamide adenine dinucleotide phosphate levels, and glutathione– glutathione disulfide ratios; decreased lung malondialdehyde levels; down-regulated the NF-&kgr;B pathway; suppressed TNF-&agr;, IL-6, and IL-8 levels in the lung tissue and serum; and attenuated histologic lung damage.”