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Discover Supplement-Drug Interactions

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Last Updated: 5 years ago

Possible Interaction: Niacin and Cpt-11

supplement:

Niacin

drug:

Cpt-11

Research Papers that Mention the Interaction

A second finding is that plasma levels of CPT-11 and SN-38 respectively increase and decrease after nicotinamide exposure, suggesting inhibition of carboxylesterase, which is necessary for the conversion of CPT-11 to its active metabolite SN-38.
Anticancer research  •  2003  |  View Paper