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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Neuroprotective Agents and Calcium Supplement

Research Papers that Mention the Interaction

The neuroprotective drug riluzole blocked sodium channels and high-voltage-activated calcium channels, thereby preventing excess stimulation of N-methyl-D-aspartate receptors and massive influx of calcium , thereby retarding spread of infarction in the brain.
The Journal of pharmacology and experimental therapeutics  •  2000  |  View Paper
Although the Ca2+ channel blocking actions of ifenprodil are observed at higher concentrations than those associated with NMDA antagonist activity, Ca2+ channel blockade may contribute, at least in part, to the established neuroprotective and anticonvulsant properties of the compound.
British journal of pharmacology  •  1994  |  View Paper