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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Neuropeptide Y
supplement:
Potassium
Research Papers that Mention the Interaction
“ NPY significantly inhibited ACh release stimulated by potassium (55 mM); by adenylate cyclase agonists forskolin (10(-6) M) and cholera toxin (10(-8) M); and by calcitonin gene-related peptide, cholecystokinin octapeptide, and vasoactive intestinal peptide (each 10(-8) M).”
Inhibition of acetylcholine release from guinea pig myenteric neurons by neuropeptide Y: GTP-binding protein mediation.“In contrast, NPY (10−6 M) produced significant inhibition of amylase release from pancreatic lobules that had been stimulated by 75 μM potassium (135 ± 11% versus 177 ± 18% of basal level) or by 25 μM veratridine (196 ± 19% versus 398 ± 152%).”
“ NPY was also seen to decrease the potassium‐induced release of norepinephrine (NE) from slices obtained from the posterior hypothalamic nucleus.”
“Addition of potassium (45 mM) resulted in a 3-fold increase in the rate of NPY release in a calcium dependent fashion.”
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