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“For TTX-S Na+ channel, taurine of the concentration > or = 10 mM shifted the activation curve in the depolarizing direction and the inactivation curve in the hyperpolarizing direction.”
“The weak modulatory effects of taurine could be of significance in vivo since depolarizing stimuli release massive amounts of taurine in developing brain tissue.”
“A depolarizing concentration (50 mM) of potassium ions caused an approximately 3.5‐fold increase in taurine release and the omission of sodium a 6‐fold enhancement.”
Journal of neuroscience research • 1987 | View Paper
“In the rabbit ear artery, taurine reduces in a reversible and dose-dependent manner the increase in vascular tone induced by a depolarizing medium (54 x lo3 p~ KCI).”