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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Calcium Supplement
Research Papers that Mention the Interaction
“ Calcium entry through L-type calcium channel and CaMKIV activation are responsible for the reduction in the expression of AMPA receptor subunits in cells cultured in depolarizing conditions.”
Membrane depolarization regulates AMPA receptor subunit expression in cerebellar granule cells in culture.“We report here that nicotine afforded neuroprotection to dopamine neurons (EC50 = 0.32 μM) but only in a situation where cytosolic Ca2+ (Ca2+cyt) was slightly and chronically elevated above control levels by concurrent depolarizing treatments.”
“Application of strong depolarizing steps (−70 to −10 mV) exceeding 200 ms or longer in duration evoked a wave of calcium that spread across the synaptic terminals of voltage‐clamped rods.”
“It is concluded that this depolarising stimulus produces, in the presence of calcium , the release by exocytosis of about one sixth of all the granules in the sinus gland, and that vacuoles are the organelle responsible for the recapture of membrane after the exocytosis.”
“ Depolarizing voltage steps from -50 mV evoked rapidly activating Ca currents, which exhibited a bell-shaped voltage dependence with peak amplitude at 0 mV. The currents were suppressed by nifedipine (5 microM), verapamil (2.5 microM), and Cd2+ (175 microM).”
“High medium calcium or addition of the sodium channel blocker tetrodotoxin (TTX) also blocked the depolarizing rectification, whereas the calcium channel antagonist diltiazem had no effect on the rectification.”
“However, prolonging presynaptic spikes or using depolarizing pulses of increasing amplitude increases Ca influx by opening more Ca channels and increasing the number of Ca domains locally triggering release.”
“ Depolarizing concentrations of potassium in the presence of calcium stimulated significant increments in release of IR-ACTH/IR-beta-endorphin by amygdala (111/105%) and cortical (162/136%) cells.”
“3 Omission of calcium ions from the medium potentiated the depolarizing actions of l‐Pro, l‐Glu and quisqualate.”
“Responses to cumulative increased Ca 2 + concentrations in depolarizing bathing medium were also blocked.”
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