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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Nerve Growth Factor
supplement:
Taurine
Research Papers that Mention the Interaction
“Mechanistically, taurine increased the expression of NGF , phosphorylation of Trka, Akt, and Bad, as well as reduced cytochrome c release from mitochondria to cytosol.”
Taurine inhibits neuron apoptosis in hippocampus of diabetic rats and high glucose exposed HT-22 cells via the NGF-Akt/Bad pathway“Mechanistically, taurine up-regulated NGF expression and phosphorylation levels of Akt and GSK3β, while, blocking activation of NGF and phosphorylation of Akt and GSK3β increased apoptosis of high glucose-exposed RSC96 cells with taurine supplement.”
Taurine protects against myelin damage of sciatic nerve in diabetic peripheral neuropathy rats by controlling apoptosis of schwann cells via NGF/Akt/GSK3β pathway.“ Taurine treatment increased BDNF and NGF expression as compared with high dose groups while Taurine seemed to have no effects on FGF.”
“ Taurine added in the medium to post‐crush explants accelerated the emission of neurites in 1–2 days, and increased the nerve growth index in a concentration‐dependent manner up to 4 mM. Greater concentration did not produce any effect on the nerve growth index.”
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