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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Nerve Growth Factor and Potassium

Research Papers that Mention the Interaction

NGF and CNTF appeared to regulate the same delayed-rectifier potassium current; in addition, NGF treatment resulted in increased levels of a second potassium current component.
Using whole-cell, perforated-patch, and single-channel recording, we found that treatment with NGF increased levels of voltage- gated sodium, calcium, and potassium currents.
The Journal of neuroscience : the official journal of the Society for Neuroscience  •  1995  |  View Paper
NGF causes a decrease in the amplitude of both calcium-dependent and -independent potassium currents, and inhibition of calcium-dependent potassium currents using CdCl(2) reproduces some, but not all, of the firing properties induced by NGF.
Journal of neurophysiology  •  2006  |  View Paper
Depletion of serum and nerve growth factor caused cell death, which was prevented by high potassium.
Neuroscience  •  1999  |  View Paper
Direct quantification of NGF protein in ACMs by the two-site ELISA method demonstrated that a high concentration of potassium enhanced NGF secretion from cultured astrocytes.
Brain Research  •  1998  |  View Paper