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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Nerve Growth Factor and Huperzine A

Research Papers that Mention the Interaction

Our previous study demonstrated that huperzine A , a selective acetylcholinesterase inhibitor, stimulates the synthesis of nerve growth factor (NGF) in cultured rat cortical astrocytes.
The present results indicate that the cytoprotective effect of huperzine A is mediated at least partly by up-regulated NGF and NGF receptors.
European journal of pharmacology  •  2005  |  View Paper
Meanwhile, huperzine A significantly increased the mRNA and protein levels of NGF , BDNF and TGF-beta(1), and potentiated phosphorylation of MAPK/ERK 1/2 in both cerebral cortex and hippocampus compared with transient cerebral ischemia and reperfusion group.
Pharmacology Biochemistry and Behavior  •  2006  |  View Paper