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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Nerve Growth Factor
supplement:
Huperzine A
Research Papers that Mention the Interaction
“Our previous study demonstrated that huperzine A , a selective acetylcholinesterase inhibitor, stimulates the synthesis of nerve growth factor (NGF) in cultured rat cortical astrocytes.”
“The present results indicate that the cytoprotective effect of huperzine A is mediated at least partly by up-regulated NGF and NGF receptors.”
Huperzine A protects SHSY5Y neuroblastoma cells against oxidative stress damage via nerve growth factor production.“Meanwhile, huperzine A significantly increased the mRNA and protein levels of NGF , BDNF and TGF-beta(1), and potentiated phosphorylation of MAPK/ERK 1/2 in both cerebral cortex and hippocampus compared with transient cerebral ischemia and reperfusion group.”
Effects of huperzine A on memory deficits and neurotrophic factors production after transient cerebral ischemia and reperfusion in mice
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