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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Neostigmine and Procaine

supplement:

Procaine

Research Papers that Mention the Interaction

The inhibitory effect of neostigmine on the hydrolysis of procaine and benzoylcholine by human plasma cholinesterase could be prevented and antagonized by tetraethylammonium, dihydrohydroxycodeinone, 14-hydroxydihydromorphinone and by tetraethylammonium, amphetamine and morphine, respectively.
The Journal of pharmacology and experimental therapeutics  •  1960  |  View Paper
Only insignificant inhibition was observed when neostigmine and procaine were added simultaneously to the plasmas.
Preincubation of various concentrations of neostigmine and Ro 2-683 with plasma, markedly influenced their inhibitory effect on the enzymatic hydrolysis of procaine.
The Journal of pharmacology and experimental therapeutics  •  1953  |  View Paper