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Last Updated: 3 years ago

Possible Interaction: Neostigmine and Niacin

supplement:

Niacin

Research Papers that Mention the Interaction

Even at recommended dose (15-50 μg/kg), neostigmine induces nicotinic (upper airway muscle weakness leading to dysphagia and upper airway obstruction, and decreased maximum inspiratory airflow) and muscarinic (blurred vision, bronchial constriction, abdominal cramping and nausea) side effects.
Neuropharmacology  •  2020  |  View Paper
It was blocked in the presence of curare and mecamylamine, two cholinergic nicotinic antagonists, and enhanced with neostigmine , a cholinesterase inhibitor.
The Journal of Neuroscience  •  1999  |  View Paper
These results indicate that neostigmine and carbaryl directly block the nicotinic AChR channel.
Brain Research  •  1997  |  View Paper
Neomistigmine increases both the nicotinic and the cholinergic (muscarinic) effects of succinyl-choline.
Revista de chirurgie, oncologie, radiologie, o.r.l., oftalmologie, stomatologie. Chirurgie  •  1976  |  View Paper
The intensity of phosphorylcholine phosphate renewal increases in the liver and skeletal muscles after introduction of both prozerin and nicotinic acid.
Ukrains'kyi biokhimichnyi zhurnal  •  1975  |  View Paper