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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Neomycin and Potassium

supplement:

Potassium

Research Papers that Mention the Interaction

Neomycin , an aminoglycoside which binds phosphoinositides, inhibits the potassium‐induced release in cortical slices with an IC50 = 0.5 ± 0.07 mM and with IC50 = 0.2 ± 0.03 mM in synaptosomes.
FEBS letters  •  1987  |  View Paper
Contractile responses to high potassium (80 mM) were inhibited by prior exposure to neomycin to a greater extent than were responses obtained with submaximal equipotent concentrations of the other vasoactive agents.
The Journal of pharmacology and experimental therapeutics  •  1974  |  View Paper
Neomycine reduces the amount of transmitter released from the motor nerve in response to a nerve volley or to a high external potassium concentration.
Acta physiologica Scandinavica  •  1962  |  View Paper