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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Naringin
drug:
Candesartan
Research Papers that Mention the Interaction
“Conclusion: This study demonstrated that increased solubilization (favored by freeze-dried solid dispersion) and efflux pump inhibition (using naringin ), the relative bioavailability of CDS can be increased, suggesting an alternative potential for improving oral bioavailability of CAN.”
“Results and discussion: We noticed 1.47-fold increase in Peff of CDS from freeze-dried CAN-loaded solid dispersions with naringin (15 mg/kg, w/w) when compared with freeze-dried solid dispersion without naringin using in-situ single pass intestinal perfusion model.”
Corroboration of naringin effects on the intestinal absorption and pharmacokinetic behavior of candesartan cilexetil solid dispersions using in-situ rat models
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