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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Naltrexone
supplement:
Intralipid
Research Papers that Mention the Interaction
“Subcutaneous administration of the non-selective opioid receptor antagonist naltrexone (0.5 or 2.0mg/kg body weight [BW]) reduced the spontaneous intake of fat emulsion ( Intralipid).”
The opioid system contributes to the acquisition of reinforcement for dietary fat but is not required for its maintenance“A strong positive relationship (r=0.91) was observed for the abilities of SCH23390 and naltrexone to inhibit intralipid intake across strains.”
“ Naltrexone significantly, dose-dependently and differentially reduced intralipid intake at all four (DBA/2), three (SWR, SJL), two (CD-1, C57BL/10) and one (C57BL/6, 129P3) of the doses tested, and also failed to affect intralipid intake in BALB/cJ mice.”
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