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Last Updated: 2 years ago

Possible Interaction: Naltrexone and Adrenocorticotropic Hormone

Research Papers that Mention the Interaction

Naltrexone also resulted in higher levels of adrenocorticotropic hormone and cortisol than placebo treatment, and levels of cortisol were negatively correlated with intensity of alcohol craving.
Psychopharmacology  •  2002  |  View Paper
Naltrexone , a relatively pure opiate antagonist, appears to have significant effects on the secretion of the gonadotropins (luteinizing hormone and follicle-stimulating hormone), adrenocorticotropin (ACTH), cortisol, and probably catecholamines.
The Journal of clinical psychiatry  •  1984  |  View Paper
ACTH level changes as a response to naltrexone in the patients were lower than that in the controls.
RESULTS Na trexone ad ministration resulted in a significant ACT H re sponse in the patients while cortisol and ACTH responses were found to be significant in the controls.
Pharmacopsychiatry  •  2014  |  View Paper
For the total sample, ACTH and cortisol significantly increased after naltrexone compared with placebo (p < .05).
Neuropsychopharmacology  •  2002  |  View Paper
NTX increased ACTH levels in alcohol drinking females in diestrus, but not in other groups.
Pharmacology Biochemistry and Behavior  •  2018  |  View Paper
Naltrexone , 0.1-1.0 mg/kg, increased ACTH levels, whereas naltrindole and clocinnamox failed to increase ACTH levels.
Psychoneuroendocrinology  •  2003  |  View Paper
Naltrexone also increased plasma concentrations of ACTH and corticosterone above basal levels at a later time in DALA-treated animals.
Naltrexone increased the adrenocortical response to ACTH in DALA-treated rats.
Endocrinology  •  1982  |  View Paper
Furthermore, naltrexone at a dose level that had no effect on motor activity blocked the suppressive effect of the high doses of ACTH but had no effect on the stimulating effect of the intermediate dose of ACTH.
European journal of pharmacology  •  1980  |  View Paper