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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Naloxone
supplement:
Calcium Supplement
Research Papers that Mention the Interaction
“This increase in Ca++ induced by morphine was blocked by simultaneous chronic administration of naloxone.”
Effects of acute and chronic morphine treatments on calcium localization and binding in brain.“The depletion of calcium by these three drugs was prevented by the opiate antagonist naloxone , whereas depletion of calcium by reserpine was unaffected by naloxone pretreatment.”
“The exposure to 10−3 M Naloxone induced significant intracellular calcium increases in cumulus cells recovered all over the year.”
Expression and localization of the µ‐opioid receptor (MOR) in the equine cumulus–oocyte complex and its involvement in the seasonal regulation of oocyte meiotic competence“ CA was significantly reduced, though not abolished, by IT injections of either naloxone , picrotoxin, or methysergide, but not by strychnine or yohimbine.”
“In cerebral arteries previously submitted to an active tone, the opioid-induced vasodilation was unchanged by naloxone , cimetidine, diphenhydramine or ouabain, whereas Ca2+ addition antagonized this effect.”
“Both the reduction in synaptic potential amplitude and the shortening of the Ca2+ action potential produced by enkephalin are blocked by naloxone.”
“This inhibitory effect can be antagonized not only by naloxone and nalorphine but also by increasing calcium concentration of the perfusion fluid of the ganglia.”
“Abstract In the guinea-pig isolated ileum, elevation of the extracellular concentration of calcium attenuated the excitatory influence of the opiate antagonist, naloxone , upon peristalsis.”
“Low calcium (0.8 mM) in the medium antagonized the potentiating action of naloxone.”
“The antagonistic effects of Ca++ and naloxone were additive in both nontolerant and tolerant animals and the apparent affinity of naloxone for its receptors, as estimated by in vivo pA2 determinations, was not altered by Ca++.”
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