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Last Updated: 3 years ago

Possible Interaction: NADH and Sorbitol

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supplement:

NADH

drug:

Sorbitol

Research Papers that Mention the Interaction

“The Km of sorbitol for PD is 1.4 mM and for NAD is 0.06 mM. NADH (Ki 0.002 mM) competitively inhibits PD in the forward direction.”

The sorbitol pathway in the human lens: aldose reductase and polyol dehydrogenase.

Investigative ophthalmology & visual science • 1981 | View Paper

“ NADH was found to inhibit competitively the rate of oxidation of ethanol and sorbitol in vitro at low levels of NAD+, but calculations showed that the degree of inhibition would probably be of minor importance in vivo.”

Metabolic interaction of ethanol and sorbitol in relation to redox state of liver cytosol in hypo-, hyper-, and euthyroid rats.

Metabolism: clinical and experimental • 1971 | View Paper

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