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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
NADH
drug:
Salicylic Acid
Research Papers that Mention the Interaction
“ NADH inhibited in a dose-response manner the binding of SA to GAPA1, validating our data.”
Deciphering the Binding of Salicylic Acid to Arabidopsis thaliana Chloroplastic GAPDH-A1“Based on results of anaerobic rapid mixing experiments, the rate of enzyme reduction by NADH is enhanced 290- and 240-fold when the hydroxylase is complexed with salicylate and benzoate (a nonsubstrate effector), respectively.”
“ Salicylate enhances, whereas benzoate slightly weakens, the NADH binding to the enzyme.”
“As observed in the stopped flow, formation of enzyme-substrate complex is very rapid; the presence of salicylate facilitates DPNH binding and determines the rate of enzyme reduction to E-FADH2.”
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