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Last Updated: 2 years ago

Possible Interaction: NADH and Octanoate

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supplement:

NADH

drug:

Octanoate

Research Papers that Mention the Interaction

“The addition of octanoate increased the content of only one inhibitor, NADH.”

The inhibition of alpha-ketoglutarate oxidation by fatty acids in rat liver mitochondria.

The Journal of biological chemistry • 1978 | View Paper

“The data suggest that octanoate addition favors the PDHa kinase reaction leading to inactivation of PDHa, and in addition causes the accumulation of NADH and acetyl-CoA which are recognized competitive inhibitors of pyruvate dehydrogenase.”

Regulation of pyruvate dehydrogenase in isolated rat liver mitochondria. Effects of octanoate, oxidation-reduction state, and adenosine triphosphate to adenosine diphosphate ratio.

The Journal of biological chemistry • 1975 | View Paper

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