“In aortas from male-young, …, and female-old mice, NADH [NAD(P)… substrate] and diethyldithiocarbamate (DDC; a SOD inhibitor) (whether applied alone or together) reduced ACh-induced endothelium-dependent relaxation (P<0.… or P<0.001) and increased ACh-induced superoxide generation (P<0.05 or P<0.001).”