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Last Updated: 2 years ago

Possible Interaction: NADH and Cupric Cation

supplement:

NADH

supplement:

Cupric Cation

Research Papers that Mention the Interaction

We demonstrated that UVA-irradiated NADH induced damage to 32P-labeled DNA fragments obtained from the p53 gene in the presence of Cu(II).
Free radical research  •  2007  |  View Paper
ESR spin-trapping experiments and mass spectrometry showed that the carbon-centered radical was formed during the reaction of NADH with Cu(II).
Formation of 8-oxo-7,8-dihydro-2'-deoxyguanosine by NADH increased with its concentration in the presence of Cu(II).
NADH , as well as other endogenous reductants, induced DNA damage in the presence of Cu(II).
Biochemistry  •  1996  |  View Paper
Using 32P-5'-end-labeled DNA fragments obtained from human p53 tumor suppressor gene and c-Ha-ras-1 protooncogene, we showed that PBQ plus NADH , and also PHQ, induced DNA damage frequently at thymine residues, in the presence of Cu(II).
Carcinogenesis  •  1999  |  View Paper
Both activities were inhibited by Cu2+ and Cd2+ with the NADH --> NAD activity being more resistant to inhibition.
Experimental parasitology  •  1997  |  View Paper
NADH and ADP (not NAD+ or ATP) enhanced LADH inactivation by Cu(II).
Free radical research  •  1995  |  View Paper
Both DCHQ and DCBQ plus NADH increased 8-oxo-7,8-dihydro-2'-deoxyguanosine in calf thymus DNA in the presence of Cu(II).
Carcinogenesis  •  1996  |  View Paper
NADH sharply increased the effects of Cu(II) and its complexes.
Acta physiologica et pharmacologica Bulgarica  •  1988  |  View Paper