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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“Abstract The inhibitory effect of urea on human and rabbit muscle M 4 -lactate dehydrogenase ( l -lactate: NAD + oxidoreductase, EC 1.1.1.27) is markedly increased in the presence of urease.”
Effect of the urea-urease system and the carbonate ion on the activities of lactate dehydrogenase isoenzymes.“ NAD greatly reduced the rate of inactivation at all the urea concentrations tested.”
Effect of NAD on flounder muscle glyceraldehyde 3-phosphate dehydrogenase“ADP, ADP-ribose, and PP-ribose-P were all noncompetitive inhibitors with Ki values of approximately 1 x 10-4 m. Inactivation of enzyme by urea can be prevented or partially reversed by the presence of NAD , NMN, or 3-acetylpyridine.”
“ NAD+ facilitates high‐yield reactivation of clostridial glutamate dehydrogenase (GDH) after unfolding in urea.”
Specificity of coenzyme analogues and fragments in promoting or impeding the refolding of clostridial glutamate dehydrogenase“IN investigating the properties of an enzymatic cycle between ammonia and nitrate1, we have now observed the enzymatic reduction of diphosphopyridine nucleotide with urea.”
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