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Discover Supplement-Drug Interactions

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Last Updated: 6 months ago

Possible Interaction: NAD and Urea

supplement:

NAD

drug:

Urea

Research Papers that Mention the Interaction

Abstract The inhibitory effect of urea on human and rabbit muscle M 4 -lactate dehydrogenase ( l -lactate: NAD + oxidoreductase, EC 1.1.1.27) is markedly increased in the presence of urease.
Biochimica et biophysica acta  •  1970  |  View Paper
NAD greatly reduced the rate of inactivation at all the urea concentrations tested.
Molecular and Cellular Biochemistry  •  2005  |  View Paper
ADP, ADP-ribose, and PP-ribose-P were all noncompetitive inhibitors with Ki values of approximately 1 x 10-4 m. Inactivation of enzyme by urea can be prevented or partially reversed by the presence of NAD , NMN, or 3-acetylpyridine.
The Journal of biological chemistry  •  1971  |  View Paper
NAD+ facilitates high‐yield reactivation of clostridial glutamate dehydrogenase (GDH) after unfolding in urea.
Protein science : a publication of the Protein Society  •  1999  |  View Paper
IN investigating the properties of an enzymatic cycle between ammonia and nitrate1, we have now observed the enzymatic reduction of diphosphopyridine nucleotide with urea.
Nature  •  1961  |  View Paper