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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
supplement:
NAD
supplement:
Tryptophan
Research Papers that Mention the Interaction
“ DL-Tryptophan induces only a slight NAD synthesis, which is reduced in adrenalectomized animals by thionine.”
Influence of DL-ethionine on the NAD content and on the activity of the poly(ADPR)synthetase in the rat liver.“Both effects are interpreted to result from formation of a charge transfer complex between the nicotinamide moiety of NAD+ and at least one of the tryptophan residues of the fragment.”
“A single intraperitoneal injection of varying amounts of tryptophan resulted in increases in hepatic tryptophan content, tryptophan oxygenase activity, NAD+ , NADPH and NADPH concentrations which were proportional to the dose of this amico acid.”
“NAm, NAc and L-T given 4 and 24 hr before thyroidectomy substantially increased thyroid NAD and NADH, while NADP and NADPH were unchanged.”
“The fluorescence decay lifetimes of FAD and Trp were prolonged in the presence of NAD+ to show that FAD would be free from the electron transfer from the neighboring Tyrs and the resonance energy transfer efficiency between Trp and FAD lowered.”
Conformational Change Near the Redox Center of Dihydrolipoamide Dehydrogenase Induced by NAD+ to Regulate the Enzyme Activity
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