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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“Digestion of submitochondrial vesicles with either trypsin, chymotrypsin, or Pronase rapidly inactivates D-beta-hydroxybutyrate dehydrogenase; the addition of NAD+ or NADH, together with dithiothreitol and increased salt (to 50 mM), decreases the rate of inactivation, and with trypsin , virtually eliminates inactivation.(ABSTRACT TRUNCATED AT 400 WORDS)”
Phospholipid protection against proteolysis of D-beta-hydroxybutyrate dehydrogenase, a lecithin-requiring enzyme.“ NAD+ partially protects against trypsin inactivation.”
“Binding of NAD+ also enhances the resistance of the fragment to trypsin or chymotrypsin.”
“Similar results are obtained with complex I preparations in which transhydrogenase activity from NADPH to NAD has been >95% inhibited by treatment of the complex with trypsin.”
Electron paramagnetic resonance studies on the reduction of the components of complex I and transhydrogenase-inhibited complex I by NADH and NADPH.
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