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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
NAD
drug:
Triiodothyronine
Research Papers that Mention the Interaction
“In primary rat hepatocytes, T3 decreased SIRT2 expression and cellular nicotinamide adenine dinucleotide (NAD) concentration, while on sirtuin activity it showed opposite effects, depending on the evaluated cell fraction.”
3-Iodothyronamine and 3,5,3′-triiodo-L-thyronine reduce SIRT1 protein expression in the HepG2 cell line“Interestingly, their T3 binding activities were inhibited by NAD+ and NADH but not by NADP+ and NADPH, whereas NAD+ was required for their ALDH activities.”
Xenopus Cytosolic Thyroid Hormone-binding Protein (xCTBP) Is Aldehyde Dehydrogenase Catalyzing the Formation of Retinoic Acid*“ NAD also induced DTT-dependent T3 binding, but was very low compared to that induced by NADP.”
“ Abstract Triiodothyronine has been found to inhibit horse liver alcohol dehydrogenase competitively with respect to NAD+ and NADH; the φ1 and φ'1 values are increased 10-fold in the presence of 10 µm triiodothyronine.”
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