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Discover Supplement-Drug Interactions

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Last Updated: a year ago

Possible Interaction: NAD and Triiodothyronine



Research Papers that Mention the Interaction

In primary rat hepatocytes, T3 decreased SIRT2 expression and cellular nicotinamide adenine dinucleotide (NAD) concentration, while on sirtuin activity it showed opposite effects, depending on the evaluated cell fraction.
Hormone molecular biology and clinical investigation  •  2020  |  View Paper
Interestingly, their T3 binding activities were inhibited by NAD+ and NADH but not by NADP+ and NADPH, whereas NAD+ was required for their ALDH activities.
The Journal of Biological Chemistry  •  1999  |  View Paper
NAD also induced DTT-dependent T3 binding, but was very low compared to that induced by NADP.
The Journal of biological chemistry  •  1989  |  View Paper
Abstract Triiodothyronine has been found to inhibit horse liver alcohol dehydrogenase competitively with respect to NAD+ and NADH; the φ1 and φ'1 values are increased 10-fold in the presence of 10 µm triiodothyronine.
The Journal of biological chemistry  •  1969  |  View Paper