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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: NAD and Triclosan



Research Papers that Mention the Interaction

Thus the dramatic enhancement in the binding affinity of both triclosan and NAD+ in the ternary complex can be explained by increased van der Waals contacts in the ternary complex, facilitated by the movement of residues 318-324 of the substrate-binding loop and the nicotinamide ring of NAD+.
The Biochemical journal  •  2004  |  View Paper
Triclosan inhibits an essential enzyme in … acid biosynthetic pathway, the reduced nicotinamide adenine dinucleotide (NADH)/reduced nicotinamide adenine dinucleotide phosphate (NADPH)-dependent enoyl-acyl carrier protein (enoyl-ACP) reductase, or FabI. In …, we used error-prone polymerase chain reaction (epPCR) to generate mutations in the S. aureus FabI enzyme.
ACS omega  •  2020  |  View Paper