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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“Importantly, treatment with ER β agonist DPN (5 nM) significantly decreased the inhibitory effect of a PTEN knockdown on tamoxifen response of both cell lines (p<0.05).”
Knockdown of PTEN decreases expression of estrogen receptor β and tamoxifen sensitivity of human breast cancer cells“Surprisingly, tamoxifen , an estrogen receptor antagonist used for breast cancer treatment, increased the activity and decreased the Km for NAD+ by about twofold in ALDH1A1.”
“The concentration of NAD in E2+ Tam 500 uteri was also significantly higher than E2 treated uteri.”
“The concentration of NAD in Tam 500 treated group was significantly higher than E2, low dose Tam and E2 + Tam 500 treated groups (P < 0.01).”
Effect of tamoxifen, estradiol 17 beta on coenzymes NAD, NADPH and the metabolism of estradiol and estrone in rabbit uterus in vivo.
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