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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: NAD and Steroids

supplement:

NAD

Research Papers that Mention the Interaction

When NAD+ is the variable component in the presence of saturated amount of steroid , the type of the inhibition is competitive in nature.
Journal of steroid biochemistry  •  1985  |  View Paper
Several reports indicate that the steroid sex hormones, namely testosterone, diethylstilbestrol and progesterone, inhibit glutamic dehydrogenase (GDH) (1) and reduce diphosphopyridine nucleotide-cytochrome c reductase (2, 3).
The Journal of investigative dermatology  •  1964  |  View Paper
Steroids with hydroxy groups at C-3 or C-20 or high concentrations of non-steroids, which can be oxidized by NAD , change the E2/E1 quotient only minimally.
Hoppe-Seyler's Zeitschrift fur physiologische Chemie  •  1975  |  View Paper
The steroids also prevented the decrease in the level of nicotinamide adenine dinucleotide which otherwise occurred in animals placed on the deficient diet.
The Journal of pharmacology and experimental therapeutics  •  1966  |  View Paper
3) It has shown in several steroid biosynthetic reactions a greater responsiveness to diphospho- and triphospho-pyridine nucleotides than the cortex.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine  •  1965  |  View Paper
When the substrate is reduced nicotinamide-adenine dinucleotide and the steroid concentration is low, oxidation is stimulated, but high steroid concentrations are inhibitory.
Biochimica et biophysica acta  •  1966  |  View Paper