Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: NAD and Salicylic Acid

supplement:

NAD

Research Papers that Mention the Interaction

Salicylic acid inhibits the oxidation of uridine-5-diphosphoglucose (UDPG) competitively with nicotinamide adenosine dinucleotide ( NAD ) and noncompetitively with UDPG.
Journal of pharmaceutical sciences  •  1969  |  View Paper
Large-scale transcriptomic analyses indicated that NAD promoted the induction of various pathogen-related genes such as the salicylic acid (SA)-responsive defence marker PR1.
The Plant journal : for cell and molecular biology  •  2012  |  View Paper
Salicylate has also been shown to inhibit malate and isocitrate dehydrogenase activities in vitro and the inhibitions were reversed by either NAD or NADP2.
Nature  •  1964  |  View Paper
We have now shown that the addition of NAD will reverse the inhibitory action of salicylate on mitochondrial malate dehydrogenase after this inhibition has become established.
Nature  •  1964  |  View Paper