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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
NAD
drug:
Pyrazinamide
Research Papers that Mention the Interaction
“It is suggested from these results that the action of pyrazinamide against tuberculosis is linked to the increase in turnover of NAD and to the increased content of NAD in the host cells.”
“The administration of pyrazinamide significantly increased the metabolites, 3-hydroxyanthranilic acid and beyond, especially quinolinic acid, nicotinamide, N1-methylnicotinamide, and N1-methyl-4-pyridone-3-carboxamide, and therefore significantly increased the conversion ratio of tryptophan to niacin and the blood NAD level.”
Effects of Dietary Pyrazinamide, an Antituberculosis Agent, on the Metabolism of Tryptophan to Niacin and of Tryptophan to Serotonin in Rats“ Pyrazinamide and nicotinamide, as well as isoniazid, suppressed the increase of NADase associated with tuberculous infection with the bacilli susceptible to these drugs.”
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