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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
NAD
drug:
Papaverine
Research Papers that Mention the Interaction
“ Abstract Papaverine was found to inhibit NAD + -linked 15-hydroxyprostaglandin dehydrogenase partially purified from guinea pig lung.”
Inhibition of 15-hydroxyprostaglandin dehydrogenase by papaverine.“SIR,-Recent reports from this laboratory (Santi, Contessa & Ferrari, 1963 ; Santi, Ferrari & Contessa, 1964) have shown that papaverine is a powerful inhibitor of the aerobic oxidation of substrates linked to nicotinamide adenine dinucleotide (NAD) in rat liver mitochondria.”
“Pre-treatment with PAP increased intracellular cAMP and nicotinamide adenine dinucleotide (NAD+) levels, restored mitochondrial membrane potential (ΔΨm), and decreased ROS and caspase 3/7 content in QUIN exposed neurons.”
Papaverine, a Phosphodiesterase 10A Inhibitor, Ameliorates Quinolinic Acid-Induced Synaptotoxicity in Human Cortical Neurons.
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