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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
NAD
Research Papers that Mention the Interaction
“When myocytes were exposed to an anthracycline concentration lower than plasma levels measured clinically (0.15 microM), doxorubicin and daunorubicin significantly decreased the intracellular ADP and NAD levels.”
Doxorubicin- and daunorubicin-induced energy deprivation and nucleotide degradation in isolated cardiomyocytes.“ Doxorubicin and daunorubicin inhibited the reduction of NAD+ to NADH during reverse electron transport.”
“The ribonucleotide kinase function of NadR was found to be feedback controlled by NAD+ under in vitro conditions and by NAD+ utilization in vivo.”
Coupling of NAD+ Biosynthesis and Nicotinamide Ribosyl Transport: Characterization of NadR Ribonucleotide Kinase Mutants of Haemophilus influenzae“This central domain mediates regulatory effects of NAD on all NadR activities.”
“In vivo genetic studies indicate that NadR represses three genes involved in the biosynthesis of NAD.”
“As NAD levels increase within the cell, the affinity of NadR for the operator regions of nadA, nadB, and pncB increases, repressing the transcription of these target genes.”
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