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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: NAD and Atorvastatin

supplement:

NAD

Research Papers that Mention the Interaction

Tested compounds have a small influence on murine endothelial cell energetics, but polyunsaturated fatty acids and atorvastatin increased intracellular NAD+ concentration that could be an important protective mechanism against endothelial cell injury.
Nucleosides, nucleotides & nucleic acids  •  2018  |  View Paper
Since combination therapy can exhibit more beneficial effects than monotherapy, we observed the protective effects of combined treatment of atorvastatin and NAD+ in EAE mice.
Taken together, these data suggested that combined treatment with NAD+ and atorvastatin could attenuate the progression of EAE by synergistic immune regulation.
The combined treatment of EAE mice with atorvastatin plus NAD+ relieved the clinical signs and histologic changes, increased the proportion of Treg cells, attenuated IL-17 production, reduced proinflammatory cytokine secretion of Th17 cells, and increased cytokine secretion of Treg cells.
Journal of Neuroimmunology  •  2021  |  View Paper