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“We show that riluzole treatment, which decreases glutamatergic neuronal excitation, decreases the synthesis and levels of both NAA and NAAG in SH-SY5Y cells in a dose and time dependant manner.”
“For example, small changes in NAA levels were detectable on repeat measurements (during 3 weeks) in patients taking Rilutek (1 6%) compared to those not (2 9%).”
Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases • 2002 | View Paper
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