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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Myricetin and Paclitaxel



Research Papers that Mention the Interaction

Nine phenolic antioxidants ((+)-catechin, (-)-epicatechin, fisetin, gallic acid, morin, myricetin , naringenin, quercetin and resveratrol) were tested for inhibition of paclitaxel metabolism.
Naunyn-Schmiedeberg's Archives of Pharmacology  •  2003  |  View Paper
It was also determined that the pre-incubation of ovarian cancer cells with a lower dose of myricetin was able to increase the cytotoxicity of paclitaxel , due to the significant downregulation of MDR-1 in these cells.
Oncology letters  •  2017  |  View Paper